Executive Director, Frontier AI

US - New York - New York

JOB ID: R-252242 LOCATION: US - New York - New York ; US - California - Los Angeles WORK LOCATION TYPE: Remote DATE POSTED: Aug. 17, 2026 CATEGORY: Information Systems SALARY RANGE: -

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Executive Director, Frontier AI

What you will do

Let’s do this. Let’s change the world. In this vital role as the Executive Director, Frontier AI you will be responsible for frontier AI strategy and the roadmap aligned to Amgen’s business, scientific, and technology priorities. You will also deliver scalable frontier AI capabilities that enable measurable impact across priority use cases.

Responsibilities:

• Portfolio prioritization and investment recommendations across reinforcement learning, multi-modal AI, model architectures, academic partnerships, and quantum AI/ML.
• Effective governance of frontier AI activities, including responsible AI, privacy, regulatory, and model-risk considerations, in partnership with CDT for frontier AI security, adversarial resilience, model assurance, and high-risk deployment governance
• External partnership outcomes, including research collaborations, talent pipelines, publications, prototypes, and applied innovation opportunities.
• Executive-level visibility into frontier AI performance, including KPIs, adoption, risks, return on investment, and strategic dependencies.
• Development and retention of top AI talent, including a strong leadership bench and culture of technical excellence.
• Cross-functional alignment with AI & Data Science, Technology, Security, R&D, Operations, Commercial, Legal, Compliance, Privacy, and Security stakeholders.
• Define and lead Amgen’s Frontier AI strategy across foundation models, multi-modal AI, advanced model architecture, academic partnerships, and quantum AI/ML.
• Build and maintain an enterprise roadmap that translates emerging AI research into scalable, high-value capabilities for R&D, Operations, Commercial, and corporate functions.
• Lead the development and application of frontier AI capabilities, including foundation models, multi-modal systems, simulation-based learning, and reinforcement learning approaches.
• Identify and prioritize high-impact use cases where frontier AI can improve scientific discovery, decision-making, productivity, and operational performance.
• Partner with AI platform, data engineering, architecture, product, domain teams, and CDT to ensure frontier AI solutions are designed for scale, reliability, security, resilience, and operational governance
• Establish technical standards for model architecture evaluation, experimentation, benchmarking, model validation, and production readiness.
• Develop Amgen’s academic and external research partnership strategy, including collaborations with leading universities, research labs, vendors, and scientific AI organizations.
• Evaluate emerging opportunities in quantum AI/ML and quantum-enabled optimization, identifying practical applications aligned to Amgen’s scientific and business priorities.
• Oversee proof-of-concept, pilot, and production pathways for frontier AI solutions, ensuring appropriate governance, documentation, monitoring, lifecycle management, and joint review processes with CDT for high-risk and security-sensitive deployments
• Build, lead, and develop a high-performing frontier AI organization, including leaders and technical ex…