Functional Genomics Senior Scientist/Assistant Director

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

Functional Genomics Senior Scientist/Assistant Director Remote or Carlsbad, CA (Hybrid) Summary We are currently seeking a highly motivated individual for the position of Senior Scientist / Assistant Director in our Functional Genomics group. This posting will be leveled as Senior Scientist or Assistant Director based on candidate’s experience and interview performance. A successful candidate will be a strategic member of a fast-paced and interactive research team contributing to the discovery of novel therapeutics. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.

Responsibilities

• Collaborate with R&D across various disease areas to analyze ‘omics data for better understanding of disease biology, preclinical model characterization, drug mechanism of action, biomarker identification, and contribute to the identification of new therapeutic targets
• Provide input as needed to experimental groups to guide study design for ‘omics-based experiments
• Use expertise as a computational biologist to integrate data from diverse sources (including transcriptome, proteome, DNA sequencing, genome structure data, and other NGS platforms)
• Work in cross-disciplinary teams and effectively communicate findings to scientific audiences with broad range of backgrounds, including biology, chemistry, and statistics
• Generalize pipelines for data integration and analysis
• Organize and document analysis strategies and results

Requirements

• Ph.D. in Computational Biology, Biological Sciences, Bioinformatics, Biostatistics, or related fields, plus 2+ years of post-PhD experience (Senior Scientist) or 3+ years of industry (Assistant Director)
• Strong track record of innovative research demonstrated in publications and oral presentations
• Familiarity with methods for advanced omics analysis such as single cell omics analysis, network inference and analysis, and machine learning
• Proficiency with Linux, git and scripting languages such as Python or R, and analytical environments/IDEs such as Jupyter, RStudio, or VSCode. Familiarity with AWS/Cloud compute is a plus.
• Excellent oral and written communication skills
• An ability to be productive and successful in a fast-paced work environment
• Knowledge in Cardiovascular, Renal, Pulmonary or Neurology fields is preferred

Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS004015

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits Full Benefits Link: ht…