Senior Product Manager, Provider and RWD Health Systems Applications

Natera’s RWD platform at the clinic connects an ecosystem of real-world evidence, molecular data, and clinical insights to deliver actionable information to physicians. We are seeking a Senior Product Manager to help build and scale physician-facing RWD applications. We seek to unlock the full potential of real-world data to improve treatment outcomes and make molecular results actionable in everyday treatment decisions. In this role, you’ll own a physician-facing RWD application for a patient’s molecular and clinical journey and workflow integrations behind it, partnering with cross-functional product teams, engineering, AI/ML teams, and clinical teams to deliver intuitive tools centered on enriched patient insights.

What You’ll Do

Advance Data Integration and Intelligence

• Collaborate with clinical product management, EMR, user experience product management, marketing, medical and a broad cross functional team to drive product strategy and roadmap,
• Drive integration of genomic tests into the platform (Signatera/ctDNA, hereditary risk, tumor/normal and NGS profiling, liquid CGP, etc.) as part of a unified oncology digitized experience.
• Work closely with AI/ML teams to build applications for patient-level insights and clinic-level insights, including cohort comparison, clinical trial matching, and cohort analytics back to individual patient care.
• Partner with legal, privacy, and security so HIPAA obligations, PHI handling, and data-governance requirements are designed into the product.

Elevate the User Experience

• Own the single- and multi-patient views that bring a patient’s molecular results and clinical events together in one physician-facing application.
• Integrate AI-powered clinical trial matching that connects patients and physicians to the most relevant investigational therapies based on molecular, clinical, and patient criteria.
• Help reduce friction points at both the provider and patient level to enroll in clinical trials.
• Partner across Natera to enable EMR/EHR integration and mobile access, ensuring seamless experiences for providers.
• Contribute to an analytics framework that captures user analytics and informs continuous product development.

Enhance the Utility of Genomic Testing

• Support delivery of a physician-facing platform that highlights therapies, tracks treatment response, and monitors disease progression in real time.
• Ship tools and functionality to aid physician collaboration.
• Connect molecular and clinical findings to relevant treatment pathways and outcomes data to make testing more actionable at the point of care.
• Partner with Product Marketing, MSL, Sales, and Clinical Operations on enablement, training, and adoption.

Launch the De-Identified Aggregated Research Platform for Health Systems

• Partner with the Health Systems BU to define, build, and launch a de-identified, aggregated research platform that turns clinic data into a health-system-wide resource for precision medicine and research.

Engage Key Stakeholders

• Engage with physicians, KOLs, and academic collaborators to translate clinical needs into features.
• Help track KPIs centered on the physician experience with RWD at the clinic.
• Support representation of RWD at the clinic at conferences, industry forums, and customer discussions as needed.

What We’re Looking For

Required:

• 5+ years of product management or related experience, including experience in healthcare, engineering, genomics, or AI/ML.
• Deep understanding of the oncology domain with direct experience building requirements and collaborating with physicians.
• Experience building clinician-facing software that fits into real clinical workflows.
• Experience delivering AI/LLM-derived clinical data into provider-facing products, including human-in-the-loop review, confidence labeling, and data transparency.
• Backlog ownership: writing and grooming user stories in Jira and driving PM perspective in Agile ceremonies (sprint planning, standups, retros).
• Hands-on with data: comfortable writing SQL (or equivalent) to check status, investigate issues, and measure outcomes, and in the habit of asking ‘is this correct, and are we ready to ship?’
• Track record of setting product KPIs and moving them, with specifics on adoption, engagement, and quality.
• Fluency in oncology / genomics clinical concepts (staging, lines of t…